網頁《Celogentins 的合成及构效关系研究》是贾彦兴为项目负责人，北京大学为依托单位的面上项目。 Celogentins是一类从青葙种子中分离得到的具有色氨酸C-2和C-6分别与组氨酸咪唑N-1和亮氨酸?-碳相连的结构独特的复杂二环多肽化合物；这些化合物对细胞微管蛋白聚合具有很强的抑制作用，其中以Celogentin C ... 網頁2014年10月21日 · Stephanotic acid methyl ester ( 12) A solution of compound 29 (80 mg, 0.14 mmol) in MeOH (3.0 mL) was degassed for 20 min, then HCO 2 NH 4 (115 …
RiPP-ing through the plant kingdom Nature Chemical Biology
網頁2000年5月1日 · Stephanotic Acid, a Novel Cyclic Pentapeptide from the Stem of Stephanotis f loribunda DOI: Authors: Kazuko Yoshikawa Tokushima Bunri University Saeko Tao Shigenobu Arihara Request full-text... 網頁2003年7月7日 · The remaining Arg-Gly fragment was then incorporated into the macrocycle by peptide bond forming reactions. The Boc-Arg(NO 2)-Gly-OH dipeptide 11 was prepared by conventional methodology from commercially available Boc-Arg(NO 2)-OH, and coupled to the amine derived by cleavage of the N-Boc-protected indole-imidazole ‘dipeptide’ 10. dr. mitesh kapadia - boston eyelid surgery
Post-translational formation of strained cyclophanes in bacteria
網頁1: stephanotic acid methyl ester [Supplementary Concept] methyl ester of the naturally occurring macrocyclic pentapeptide stephanotic acid containing an unusual beta … 網頁2006年9月6日 · Coupling of ortho -iodoaniline with aldehyde is realized under mild ligandless conditions [Pd (OAc) 2, DABCO, DMF, 85 °C], whereas X-Phos is found to be the ligand of choice for coupling reactions involving ortho -chloroanilines/ ortho … 網頁During their synthesis of stephanotic acid, Moody et al. [52] developed an independent approach towards phosphoryl glycine-containing peptides based on a rhodium-catalyzed NH insertion of the corresponding carbenes into amino acid amides (Scheme 1.9) [53]. dr mitha mohammed