Phospho-4ebp1
WebMolecular Cell, Vol. 12, 889–901, October, 2003, Copyright 2003 by Cell Press Oncogenic Ras and Akt Signaling Contribute to Glioblastoma Formation by Differential WebPhospho-4EBP1 (Thr37, Thr46) Polyclonal Antibody Advanced Verification This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated. …
Phospho-4ebp1
Did you know?
WebPhospho-4EBP1 (Thr46) Antibody (44-1170G) in ICC/IF Immunofluorescence analysis of 4EBP1 (pT46) was done on 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 15 minutes, permeabilized with 0.25% Triton™ X-100 for 10 minutes, and blocked with 5% BSA for 1 hour at room temperature. WebPhospho-4E-BP1 (Thr37/46) (236B4) Rabbit mAb detects endogenous levels of 4E-BP1 only when phosphorylated at Thr37 and/or Thr46. This antibody may cross-react with 4E-BP2 and 4E-BP3 when phosphorylated at equivalent sites. Non-specific staining has been observed in mitotic cells by immunofluorescence Phospho-4E-BP1 (Thr37/46) (236B4) Rabbit mAb
WebTranslation repressor protein 4E-BP1 (also known as PHAS-1) inhibits cap-dependent translation by binding to the translation initiation factor eIF4E. Hyperphosphorylation of 4E-BP1 disrupts this interaction and results in activation of cap-dependent translation (1). Both the PI3 kinase/Akt pathway and FRAP/mTOR kinase regulate 4E-BP1 activity ... WebJul 7, 2016 · Cell proliferation, p4EBP1 and pS6RP were strongly suppressed by GSK-3 inhibition. Rapamycin and LY294002 sufficiently decreased pS6RP, but only moderately …
WebOur 4EBP1 polyclonal, monoclonal, recombinant monoclonal and recombinant polyclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by … WebImmunoprecipitation of Phospho-4E-BP1 (Ser65) from MCF-7 cell extracts. Cells were starved for 24 hours in serum-free medium and underwent a 1 hour amino acid deprivation. Amino acids were replenished for 1 hour. Cells were then treated with 100 nM insulin for 30 minutes. Lane 1 is 10% input, lane 2 is Normal Rabbit IgG #2729, and lane 3 is ...
WebPhospho-4EBP1 (Thr37, Thr46) Antibody (PA5-114544) in ICC/IF Immunocytochemistry analysis of Phospho-4EBP1 (Thr37, Thr46) in HeLa cells (heat shock treatment). Samples …
WebEu-phospho-4EBP1 (25 µL) Acc-phospho-4EBP1 (100 µL) 4EBP1 control lysate (200 µL) 5X Lysis Buffer 2 (5 mL) 10X TR-FRET Detection buffer (250 µL) 100X Phosphatase Inhibitor Cocktail (250 µL) Reactivity Human US $ 1,199.00 Add to cart BioAuxilium sells direct to Canada- and US-based customers only. oratorienhof leuvenWebApr 14, 2024 · Neuropathic pain caused by trigeminal nerve injury is a typical refractory orofacial chronic pain accompanied by the development of hyperalgesia and allodynia. We previously demonstrated that the mammalian target of rapamycin (mTOR) inhibitor rapamycin suppressed orofacial formalin injection-induced nociception; however, the … oratorio for living things ticketsWeb丁香通为您提供4EBP1antibod商品详情介绍:价格:询价,货号:GTX83226,CAS号:详见说明书,品牌:慧嘉生物,产地:USA,详见丁香通4EBP1antibod商品详情页; oratorio iseo facebookWebApr 1, 2024 · We also engineered a mutant 4E-BP1 that cannot be phosphorylated by mTOR resembling de-phospho-Thr46-4E-BP1, and generated HNSCC cells expressing this mutant in a tetracycline-inducible fashion. Expression of 4E-BP1 M was sufficient to disrupt the function of the translation–initiation complex, and resulted in tumor regression in HNSCC ... oratorio for living things reviewsWebJan 2, 2024 · Here we demonstrate that rapamycin-insensitive mTORC1 signaling via 4E-BP1 is a critical pathway for TGF-β 1 stimulated collagen synthesis in human lung fibroblasts, whereas canonical PI3K/Akt... iplayer fred dibnahWebPhospho-4E-BP1 (Thr37/46) (236B4) Rabbit mAb detects endogenous levels of 4E-BP1 only when phosphorylated at Thr37 and/or Thr46. This antibody may cross-react with 4E-BP2 … oratorio silk tapered lampshadeWebGeneral notes. This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility. - Improved sensitivity and specificity. - Long-term security of supply. - Animal-free production. For more information see here. iplayer four lives