WebConclusions: Folic acid supplementation should be initiated each time phenytoin therapy commences because of the hypothesized cofactor mechanism, decreased adverse … WebFeb 23, 2024 · The decrease of Folate concentration was due to the effect of Phenytoin mainly on inhibiting the intestinal absorption of Folate 1. The result showed that the mean …
Phenytoin-Folic Acid Interaction: A Lesson to be Learned : Clinical ...
WebOne of the first symptoms of folate deficiency is extreme tiredness ( fatigue ). Other symptoms may include: Anemia symptoms Paleness. Shortness of breath (dyspnea). Irritability. Dizziness. Oral symptoms Tender, red tongue. Mouth sores or mouth ulcers. Reduced sense of taste. Neurological symptoms Memory loss. Difficulty concentrating. … WebJan 15, 2024 · Phenytoin is available in oral and intravenous (IV) formulations. The oral form is completely absorbed after ingestion. Its absorption is rapid with peak plasma … book on hiking trails washington
Folate-deficiency anemia: MedlinePlus Medical Encyclopedia
WebMar 21, 2024 · Some medications may lead to a folate deficiency, such as: 12 Azulfidine (sulfasalazine) Bactrim (trimethoprim-sulfamethoxazole) Dilantin (phenytoin) Trexall … WebFeb 13, 2024 · Taking folic acid with fosphenytoin (Cerebyx), phenytoin (Dilantin, Phenytek) or primidone (Mysoline) might decrease the drug's concentration in your blood. Barbiturates. Taking folic acid with a drug that acts as a central nervous system depressant (barbiturate) might decrease the drug's effectiveness. Methotrexate (Trexall). WebLow folate intake, malabsorption as a result of gastrointestinal diseases, pregnancy, and drugs such as phenytoin are causes of folate deficiency. 4 Folate deficiency is also associated with chronic alcoholism. 5 Folate and vitamin B 12 deficiency impair DNA synthesis, causing macrocytic anemias. book on history of islam