WebIn this study, investigation of the role of the endothelial PAS domain-containing protein 1 (EPAS1), a regulatory α subunit of the hypoxia-inducible factor complex, during angiotensin II-induced hypertensive nephropathy provided novel insights into FSGS pathogenesis in the absence of a primary podocyte abnormality. Webendothelial PAS domain protein 1 Normal Function The EPAS1 gene, often known as HIF2A, provides instructions for making a protein called hypoxia-inducible factor 2-alpha …

ndothelial PAS domain protein 1 . EPAS1), a transcription …

WebNM_001430.5(EPAS1):c.*833G>A AND Erythrocytosis, familial, 4 Clinical significance: Uncertain significance (Last evaluated: Jan 12, 2024) Review status: 1 star out of maximum of 4 stars WebApr 9, 2024 · Our results showed that ZnO-NR treatments increased cell death through ROS accumulation, HIF-1α and endothelial PAS domain protein 1 (EPAS1) activation, and induction of autophagy and mitophagy in both cell lines. These results, while on one side, confirmed that ZnO-NRs can be used to reduce cancer growth, on the other side, raised … dairy food safety vic

EPAS1 (Endothelial PAS Domain Protein 1) Orchestrates …

WebApr 4, 2024 · EPAS1 endothelial PAS domain protein 1 [ Homo sapiens (human) ] Gene ID: 2034, updated on 12-Feb-2024 Download Datasets Summary Official Symbol EPAS1 … Endothelial PAS domain-containing protein 1 (EPAS1, also known as hypoxia-inducible factor-2alpha (HIF-2α)) is a protein that is encoded by the EPAS1 gene in mammals. It is a type of hypoxia-inducible factor, a group of transcription factors involved in the physiological response to oxygen concentration. … See more The EPAS1 gene encodes one subunit of a transcription factor involved in the induction of genes regulated by oxygen, and which is induced as oxygen concentration falls (hypoxia). The protein contains a See more A high percentage of Tibetans carry an allele of EPAS1 that improves oxygen transport. The beneficial allele is also found in the extinct Denisovan genome, suggesting that it … See more EPAS1 has been shown to interact with aryl hydrocarbon receptor nuclear translocator and ARNTL. See more • EPAS1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) This article … See more Mutations in the EPAS1 gene are related to early-onset neuroendocrine tumors such as paragangliomas, somatostatinomas See more • Brahimi-Horn MC, Pouysségur J (2005). "The hypoxia-inducible factor and tumor progression along the angiogenic pathway". International Review of Cytology. 242: 157–213. doi:10.1016/S0074-7696(04)42004-X. ISBN 9780123646460 See more dairy foods publication