Circshoc2
WebOct 5, 2024 · CircRNAs are stable in eukaryotic cells. CircRNAs can interact with RNA-binding proteins and modulate mRNA stability, and gene transcription. It is proved that endogenous circRNAs can be translated into proteins ( Chen and Yang, 2015; Meng et al., 2024 ). Moreover, like lncRNAs, circRNAs also have MREs.
Circshoc2
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WebMar 1, 2024 · Exosome-Shuttled circSHOC2 from IPASs Regulates Neuronal Autophagy and Ameliorates Ischemic Brain Injury via the miR-7670-3p/SIRT1 Axis 2024, Molecular Therapy - Nucleic Acids Show abstract New progress in the approaches for blood–brain barrier protection in acute ischemic stroke 2024, Brain Research Bulletin Show abstract WebAug 12, 2024 · To determine the authenticity of circSHOC2, the sequence of circSHOC2 was analyzed using Sanger Sequencing, which was performed by Synbio Technologies …
WebFurthermore, circSHOC2 regulates SIRT1 expression by sponging miR-7670-3p. Transfection with a siRNA-7670-3p and incubation with circSHOC2 extracellular vesicles attenuated ischemia-induced neuronal apoptosis in vivo and in vitro, while silencing SIRT1 reversed the protective effects of exosomal circSHOC2 on hypoxic brain neurons. Web维普中文期刊服务平台,是重庆维普资讯有限公司标准化产品之一,本平台以《中文科技期刊数据库》为数据基础,通过对国内出版发行的15000余种科技期刊、7000万篇期刊全文进行内容组织和引文分析,为高校图书馆、情报所、科研机构及企业用户提供一站式文献服务。
WebThe research investigated the function and mechanism of circRNA circSHOC2 in pyroptosis of vascular endothelial cells and suggested the potential roles of circSHoc2 on HG-induced vascular endothelium cells in vitro condition, providing new insights for cardiovascular system complications of diabetes. Emerging evidence indicates that pyroptosis … WebThe aim of the present study was to investigate the neuroprotective roles and mechanisms of the circular RNA circSHOC2 in ischemic-preconditioned astrocyte-derived exosomes (IPAS-EXOs) against...
WebSep 26, 2024 · Overexpression of circSHOC2 in neurons yielded the same protective effects as those from IPAS-EXOs in vitro, and similar results were also observed in the …
WebE RNA-binding protein immunoprecipitation (RIP) following PCR assays showed the molecular binding of circSHOC2 and miR-145. F RT-PCR was performed to detect the miR-145 level in high glucose (HG ... ion blow gunWebApr 26, 2024 · Overexpression of circSHOC2 in neurons yielded the same protective effects as those from ischemic-preconditioned astrocyte-EVs in vitro, and similar results were also observed in MCAO mice by sponging miR-7670-3p, which regulates SIRT1 expression (Chen et al., 2024b). In addition to circRNAs, miRNAs are the most commonly reported … ontario green button regulationWebDiseases: EV Sources: Specific substrates: Modification methods: Modified EVs: Biological effects: Ref. SCI: BMSC: miR-26a: Cell transfection: miR-26a-EV: Axonal ... ion blowerWebCircular RNA circSHOC2 (hsa_circ_0092670) is located at chromosome 10, whose genomic length is 13,454, with abundant expression in the cerebellum, occipital lobe, frontal cortex, and parietal lobe. A recent study from Chen’s team declared that circular RNA circSHOC2 in ischemic-preconditioned astrocyte-derived exosomes (IPAS-EXOs) could ... ontario greenhouse vegetable growers ontarioWebApr 1, 2024 · CircSHOC2 significantly upregulated: CircSHOC2/miR-7670-3p/SIRT1 axis: Circshoc2 inhibits neuronal apoptosis and alleviates neuronal damage: Chen W et al. Common RNA-SEQ data of human IS focus tissues and controls: hsa-Circ 0078299 and FXN — Neuroprotection and brain recovery: Silva P W et al. There were 170 AIS … ontario green investment fundWebTo determine the authenticity of circSHOC2, the sequence of circSHOC2 was analyzed using Sanger Sequencing, which was performed by Synbio Technologies (Suzhou, … ontario greenhouse gas emissionsWebDec 1, 2024 · Studies have investigated the neuroprotective effect and mechanisms of circSHOC2 in ischemic preconditioned astrocyte-derived exosomes (IPAS-EXOs) in cerebral ischemia. When astrocytes were deprived of glucose and oxygen for 6 h, circSHOC2 was significantly up-regulated in the exosomes derived from the ischemic … ion blow gun agz iii